| abstract |
Disclosed is an agent for prevention and treatment of acute renal failure which contains a hydantoin derivative represented by the general formula below as an active ingredient. Among such compounds, (2S,4S)-6-fluoro-2’,5’-dioxospiro[chroman- 4,4’-imidazolidine]-2-carboxamide is particularly preferable. (formula) (In the formula, X represents a halogen atom or a hydrogen atom, and R1 and R2 independently represent a hydrogen atom or an optionally substituted C1-6 alkyl group or the like.) |