Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6042509de7544921c96de43b9da1438 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_825e4c1ce464ea1e02166f029ac57aef |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
filingDate |
2006-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fde94dd1b52ae602434481ead9b8e14 |
publicationDate |
2007-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2007042470-A2 |
titleOfInvention |
Antithrombotic compound |
abstract |
The present invention relates compounds of the formula I : oligosaccharide-spacer-GpIIb/IIIa antagonist I, wherein the oligosaccharide is a negatively charged pentasaccharide residue of the structure (I), the charge being compensated by positively charged counterions; the spacer is an essentially pharmacologically inactive linking residue of a length of 15-50 atoms; the GpIIb/IIIa antagonist is a residue derived from tirofiban or an analogue thereof; or a pharmaceutically acceptable salt thereof or a prodrug or a solvate thereof. The compounds of the invention have antithrombotic activity and can be used in treating or preventing thrombotic diseases. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9463249-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2398482-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8846103-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8569231-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9566297-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10398781-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2398482-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9074015-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8933207-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8940690-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8906850-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8623345-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011073408-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9050370-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9068013-B2 |
priorityDate |
2005-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |