abstract |
There has been required a fused protein composition of the Fc domain of an antibody which has an enhanced effector function and is useful as a drug. Thus it is intended to provide a composition comprising a fused protein molecule of the Fc domain of an antibody which has an N-glycoside-binding complex sugar chain in the Fc domain, wherein the N-glycoside-binding complex sugar chain is a sugar chain having no fucose attached to N-acetylglucosamine at the reducing end of the sugar chain; a transformant producing this fused protein composition; a process for producing the fused protein composition; and a drug containing the fused protein composition. |