| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d70e6e08cf16f77bd664a626e44a6abe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_430c89d97f6839f5364904e710af9704 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70571 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78 |
| filingDate |
2004-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f10281e2b8e107965cae6315046a339 |
| publicationDate |
2004-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2004092385-A1 |
| titleOfInvention |
METHOD OF DETECTING β3 ADRENALINE RECEPTOR MUTANT GENE AND NUCLEIC ACID PROBE AND KIT THEREFOR |
| abstract |
A nucleic acid probe in which a region containing a mutation in a base sequence bringing about a mutation of substituting tryptophan at the 64-position of the amino acid sequence of β3 adrenaline receptor into arginine (B3AR Trp64Arg mutation) is amplified by PCR and one end is labeled with a fluorescent dye and which shows a decrease in the fluorescence of the fluorescent dye upon hybridization. This probe has a base sequence starting with the base at the 183-position in the base sequence represented by SEQ ID NO:1, consisting of 8 to 30 bases and being labeled at the 5’-end with a fluorescent dye, or a base sequence ending with the base at the 196-position in the base sequence represented by SEQ ID NO:2, consisting of 7 to 30 bases and being labeled at the 3’-end with a fluorescent dye. Using this nucleic acid probe, the fluorescence of the fluorescent dye is measured to conduct melting curve analysis. Based on the results of the melting curve analysis, a mutation is detected. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008066164-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8021845-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2450444-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-5279492-B2 |
| priorityDate |
2003-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |