| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0920dabb2295fe731253aede0d43ccb8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_269b0b2f24ff2790756289fa3ac1b9fd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94dc1dd7bb8a9709a568d348fc3da581
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_96a2842b81a1eb6732fd8c376cde6204 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
| filingDate |
2001-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f860e19daa6c588a275caa6b7caad0d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_522fcc996cdc2c32aa5211efea40d486
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ee1e0716385d37ac8eedd1feedfdc37 |
| publicationDate |
2002-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0246205-A2 |
| titleOfInvention |
Process for the preparation of phosphorothionate oligonucleotides |
| abstract |
A process for the synthesis of phosphorothioate oligonucleotides is provided which comprises assembling an aligonucleotide bound to to a solid support in the presence of acetonitrile; prior to cleaving the oligonucleotide from the solid support removing the acetonitrile; and cleaving the oligonucleotide from the solid support. The process is particularly suited to the large scale synthesis of nucleotides. The acetonitrile may be removed from the solid support by one or both to drying and by washing with solvents. Preferred washing solvents comprise trialkylamines. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1660512-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7635772-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004055036-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006512411-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012059510-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1660512-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-100384864-C |
| priorityDate |
2000-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |