Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_269b0b2f24ff2790756289fa3ac1b9fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_305c0fcd7772e8a08daf683dbed5b780 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-06 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B50-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
filingDate |
2003-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f53947394ad90289420a0f3b53ba5ae6 |
publicationDate |
2004-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2004055036-A1 |
titleOfInvention |
Process for the preparation of oligonucleotides |
abstract |
A process for the synthesis of an oligonucleotide is provided in which an oligonucleotide is assembled on a swellable solid support using the phosphoramidite approach in the presence of an activator, wherein the activator is not tetrazole or a substituted tetrazole. Preferred activators are pyridinium, imidazolinium and benzimidazolinium salts; benzotriazole and derivatives thereof; and saccharin or a saccharin derivative. Preferred swellable solid supports comprise functionalised polystyrene, partially hydrolysed polyvinylacetate or poly(acrylamide). |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012059510-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022132681-A1 |
priorityDate |
2002-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |