abstract |
A compound of formula (I) and pharmaceutically acceptable derivatives thereof, in which R1 is H or C¿1-6?alkyl; R?2 is R3¿ is C¿1-6?alkyl or NH2. Compounds of formula (I) are potent and selective inhibitors of COX-2 and are of use in the treatment of the pain, fever, inflammation of a variety of conditions and diseases. |