| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3adf44a758133afcf111ef4dcaaf3ad3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4207bffa296c39b1619ebfb1287f98ea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff81a650b70e913d3b2524b45e4c7320
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3f221ff601a630ca8afbb9d3a6a30d3e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43518
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43513 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
| filingDate |
2001-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c073638585cbb05e6d0924b9614193c6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a1bfe1b6c5fc5cbba9b751d41a1fa64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_510a680faedb13829428d35bfd1402ce |
| publicationDate |
2001-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0176618-A1 |
| titleOfInvention |
Mechanically activated channel blocker |
| abstract |
The present invention discloses a 35 amino acid peptide (SEQ ID NO:1) that blocks stretch-activated ion channels. The peptide, designated as GsMTx-4, is present in the venom of the spider Grammostola spatulata. The present invention also discloses a method of purifying the peptide GsMTx-4 from the spider venom and a method for inhibition of stretch activated ion channels in a cell. This peptide can be used for the treatment of cardiac arrhytmias. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006014493-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006014493-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004085647-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9211313-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012184491-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005023284-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7259145-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7396816-B2 |
| priorityDate |
2000-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |