http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9724398-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0853f14a64b16d1710f4315d150da980 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-552 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0003 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate | 2015-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d6a4bd268d143f20b73a1ae8ca41a72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b7112ce6cb7e62bb9afb8f49428f349 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ed8997f04556aac72a1eeb805a80ca8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31a6952d37f0fb6373d5dd9fe6b996c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b32fe1273aec28b67918e149119e3a74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c618fa138ed95b1d1b5e0babe29e779 |
| publicationDate | 2017-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-9724398-B2 |
| titleOfInvention | Combination of protein forms for hornfly vaccination |
| abstract | Thrombostasin is an anti-clotting protein found in saliva of Haematobia irritans . Disclosed herein are studies testing blood uptake of horn flies feeding on cattle which confirm the association of ts genotype with blood uptake of horn flies. Blood uptake volumes of homozygous ts10 horn flies were lower than those of other ts genotypes when fed on control cattle. Cattle vaccinated with recombinant protein isoforms rTS9 or rTB8 resisted horn fly feeding by yielding lower blood volumes compared to flies feeding on control cattle. The impact of vaccination varied by ts genotype of flies. Cattle vaccinated with isoforms rTS9 resisted flies of ts2, ts9, and tb8 genotype. Vaccination with isoforms rTB8 produced resistance to ts8, ts9 and tb8 genotype flies. Horn flies of genotype ts10 were not affected with either TS isoforms and fed well on rTS9 and rTB9 vaccinated as on control-vaccinated cattle. |
| priorityDate | 2011-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 95.