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filingDate 2012-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2016-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9347041-B2
titleOfInvention Method for preparing corneal endothelial cell
abstract The present invention relates to a method for preparing corneal endothelial progenitor cells by adherent culturing a cell population isolated from corneal endothelial cell tissue at a low density by using a serum-free medium. The present invention also relates to a method for preparing corneal endothelial cells by differentiation-inducing the corneal endothelial progenitor cells obtained by the aforementioned method. According to the present invention, corneal endothelial progenitor cells can be selectively grown from a corneal tissue-derived cell population, and corneal endothelial cells obtained by inducing the corneal endothelial progenitor cells can be applied to treatment of corneal endothelial diseases. As a result, problems of corneal transplantation such as shortage of donors and occurrence of rejection can be solved.
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