Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41068ee09a6c0d27e534864c161e60aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2845c719a4fab59c10e8acc16cb8cc4b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_65721f9ad48b62ada112de041ce60309 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb087cf1ad57c93d61766cd4d626e70f |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
filingDate |
2009-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3be24db472f7af22edc1b2e2c3af954 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bafbf966492a9752fb978cb09b2490ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6faf5ef270936906e067afcf33fe168 |
publicationDate |
2013-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8546532-B2 |
titleOfInvention |
Synthesis of directed sequence polymer compositions and antibodies thereof for the treatment of protein conformational disorders |
abstract |
The instant invention comprises a process for the solid phase synthesis of directed epitope peptide mixtures useful in the treatment and diagnosis of protein conformational disorders, such process defined by a set of rules regarding the identity and the frequency of occurrence of amino acids that substitute a base or native amino acid of a known epitope. The resulting composition is a mixture of related peptides for therapeutic use. The invention also pertains to the process of generating antibodies using the directed epitope peptide mixtures as the antigens, and antibodies generated by such process, useful in the treatment and diagnostics of the said protein conformational disorder. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11307941-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11301339-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11226874-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11625307-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11656954-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10406197-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9533037-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011129497-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3166966-A1 |
priorityDate |
2008-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |