| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95883a083bdf08f5d19baab04452d6e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e4e1cb28f43ff0b4c3ae15cc6b785165
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e145b10bf5c2b2f1d979790f2301a91e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-515 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783 |
| filingDate |
2005-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a4f4658204c587d13fea6b70a6f4478
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69bddb80099254a3d261033056bff4e6 |
| publicationDate |
2006-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2006050138-A2 |
| titleOfInvention |
Methods of generating antigen-specific cd4+cd25+ regulatory t cells, compositions and methods of use |
| abstract |
The present invention provides methods for generating mammalian T cell populations comprising antigen-specific CD4+CD25+ regulatory T cells from freshly isolated CD4+CD25- T cells. The method comprises selecting CD4+CD25- T cells from a sample obtained from a mammalian subject; determining the MHC Class II type of the subject; inducing the generation of antigen-specific regulatory T cells by contacting the isolated CD4+CD25- T cells in a culture vessel with an induction agent for a time period sufficient to generate antigen-specific CD4+CD25+ regulatory T cells; and selecting the CD4+CD25+ antigen-specific regulatory T cells by sorting the cells in the induction culture with a selection agent comprising at least one artificial multimeric MHC Class II/peptide complex that corresponds to the MHC Class II type of the subject. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8658159-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2205720-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2492234-C2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008098787-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008098787-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015063176-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9517253-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009073599-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9480715-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020308543-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2205720-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8546532-B2 |
| priorityDate |
2004-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |