Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b56c3aefca9f07003638d14ed1da78bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9df8bc18e7b2713c1bcdc3f3beae21ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09ac6322f351983cac1af60bf957ecd9 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate |
2003-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_823fb9a986db1372fdcff7f7543c5d31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f06d39f13c9b110b0cf11195fc6f8ad9 |
publicationDate |
2004-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2004009625-A2 |
titleOfInvention |
PEPTIDES AND PEPTIDE DERIVATIVES FOR THE TREATMENT OF α-SYNUCLEIN-RELATED DISEASES |
abstract |
The invention provides peptides which comprise a sequence of three to twelve contiguous amino acid residues (the 'contiguous sequence') from amino acid residues 61 to 100 of naturally occurring α-synuclein. The contiguous sequence is linked at its N-terminal and/or C-terminal end to one or more further amino acid residue(s) which are more hydrophilic than the amino acid residue to which that end of the sequence is linked in naturally occurring α-synuclein. The invention also provides derivatives and analogues of such peptides. Peptides, derivatives or analogues of the invention are of use in prevention of α-synuclein oligomerisation and/or aggregation associated with the diseases known as the synucleinopathies. As a result peptides according to the invention are susceptible of use in the preparation of medicaments, and also in methods of treatment, for prevention and/or treatment of synucleinopathies. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113727701-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009027690-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7910333-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8506959-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9034337-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010284934-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9095556-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9879071-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009012275-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010537962-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8613905-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8697082-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8673593-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7919088-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11534484-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106854233-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107261133-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7674599-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106854233-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8546532-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2766711-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8092801-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8147833-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7727957-B2 |
priorityDate |
2002-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |