http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8114832-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7774ff76e8ffde6e5f749ccef64d5722 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5d11ede84a55c6cd4eaa8c94c0e319d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a08da19f411041a91d566625018d89c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6842 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-00 |
| filingDate | 2005-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_180ee97c5e198b176823a7acc7c6df14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07d6567bb471780f2bba6b645d4e840e |
| publicationDate | 2012-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8114832-B2 |
| titleOfInvention | Method for detecting and/or removing a protein comprising a cross-beta structure from a pharmaceutical composition |
| abstract | The invention relates to the detection and/or removal of conformationally altered proteins and/or molecules comprising a cross-β structure from a pharmaceutical composition. Disclosed is that unwanted and/or toxic side effects of pharmaceuticals are caused by proteins present in the pharmaceutical and adopting a cross-β structure conformation. Further disclosed is a method for detecting a protein in a pharmaceutical composition, the method comprising: contacting the pharmaceutical composition or any of its constituents comprising a protein with at least one cross-β structure-binding compound resulting in a bound protein and/or peptide comprising a cross-β structure and; detecting whether bound protein and/or peptide comprising a cross-β structure are present in the pharmaceutical composition or any of its constituents comprising a protein. Further described are methods for removing cross-β structures from a pharmaceutical composition and controlling the manufacture of a pharmaceutical composition. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020204983-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006045853-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010310462-A1 |
| priorityDate | 2005-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 249.