| abstract |
The invention relates to cross-β structures and the biologicalnrole of these cross-β structures. Methods for modulatingnextracellular protein degradation and/or protein clearance or forndiminishing plaques involved in conformational diseases by modulatingncross-β structure formation and/or tissue plasminogen activatorn(tPA)-like activity are disclosed, as well as diagnostic methods bynvisualising cross-β structures. |