http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8008085-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_430c89d97f6839f5364904e710af9704 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-805 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-25 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-721 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
filingDate | 2008-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2011-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3aaed79a481d515355f8d7a569ac569b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82de806180ce2032e4d540c50cddb628 |
publicationDate | 2011-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-8008085-B2 |
titleOfInvention | Method of measuring HbA1c |
abstract | A method of measuring HbA1c is provided that, even with a whole blood sample after storage, measurement accuracy substantially equal to a whole blood sample right after collection can be maintained. Whole blood is stored in a presence of a glycolytic inhibitor and protease is added to the stored whole blood sample to cleave hemoglobin in the whole blood sample. Then a glycated part of a hemoglobin fragment thereby obtained is treated with fructosyl amine oxidase. Thereafter, a glycation degree of HbA1c is determined by measuring a redox reaction between the glycated part and the fructosyl amine oxidase. Further, instead of storage of the whole blood in a presence of the glycolytic inhibitor, a strong electrolyte substance such as KCl, K 2 SO 4 , KNO, NaCl, Na 2 SO 4 , NaNO, MgCl 2 , MgSO 4 , Mg(NO) 2 , etc. is added to the whole blood after storage and a protease treatment is performed in a presence of the strong electrolyte substance. According to these methods, fluctuation in a measurement value of HbA1c due to storage of the whole blood can be avoided. |
priorityDate | 2007-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 192.