http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7993848-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_99fa97ee0c253bca8385df24f88f5c67 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-31 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
| filingDate | 2006-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc10ec4f42359e6492e9fa08e67f7456 |
| publicationDate | 2011-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7993848-B2 |
| titleOfInvention | Staphylococcus protein A domain mutants that bind to TNF-α |
| abstract | A TNF-α binding polypeptide is provided, which is related to a domain of staphylococcal protein A (SPA) in that the sequence of the polypeptide corresponds to the sequence of the SPA domain having 1 to about 20 substitution mutations. Nucleic acid encoding the polypeptide, expression vector comprising the nucleic acid, and host cell comprising the expression vector are also provided. Also provided are methods comprising a step of affinity separation or detection, in which step a polypeptide according to the invention is used. Such methods may be used for reducing the content of TNF-α in a body fluid. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10189891-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8754198-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012282700-A1 |
| priorityDate | 2005-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 401.