| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5161f46a47332fe64c7e4abf698b6e99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ce8cd065b31d33b5f32ed921e2064ab7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_06f160b24b7a2f9b5ec41578ecc38d3b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8226e858c8d28b53988c3a273f9105c6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b567e4f54131fb2d8808ff293880dd9d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_72e263b410a313c4b80bc09748dc43e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08755b41a422b3d1f8d28c82d1c8257e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_77f8f0c84f00a3d1d8950f724374e3bc |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-035 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-525 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-525 |
| filingDate |
2011-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_597f389aa488bf65bdead3644dba7e9a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6974a681075f363e9b1e401b50705d55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c8508a848ce719a30a8c8625d5eb0a5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b46d799bb6fcdf74e1f765477e3aacc2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40ee81603bcb2a929bf76181103b3b10 |
| publicationDate |
2014-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8754198-B2 |
| titleOfInvention |
Modified food grade microorganism for treatment of inflammatory bowel disease |
| abstract |
The present invention relates to microorganisms that express, or have attached to their surface, a TNFα binding polypeptide. Peptides expressed or attached on the surface of microorganism are more resistant to chemical and enzymatic degradation in the gastrointestinal tract. Such microorganisms are capable of binding TNFα and therefore reducing the content of free TNFα and alleviating its pro-inflammatory effects in the gut. The invention also relates to the use of such microorganisms as medicament in the treatment of inflammatory bowel disease. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021070823-A1 |
| priorityDate |
2010-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |