| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_77f8f0c84f00a3d1d8950f724374e3bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8226e858c8d28b53988c3a273f9105c6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_06f160b24b7a2f9b5ec41578ecc38d3b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08755b41a422b3d1f8d28c82d1c8257e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5161f46a47332fe64c7e4abf698b6e99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b567e4f54131fb2d8808ff293880dd9d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_72e263b410a313c4b80bc09748dc43e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ce8cd065b31d33b5f32ed921e2064ab7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-035 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-525 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
| filingDate |
2011-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8350fa2c88a69235af33149ad3892a7a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b02bc62dad5dc5da3c43ee9e0470ed8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bf3da107577b30303fa5594c0ca669b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e93bee8fff4e342b8a6a2a2474806bfb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f7238164614405d8a726c5c7d7bda76 |
| publicationDate |
2012-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012282700-A1 |
| titleOfInvention |
Modified food grade microorganism for treatment of inflammatory bowel disease |
| abstract |
The present invention relates to microorganisms that express, or have attached to their surface, a TNFα binding polypeptide. Peptides expressed or attached on the surface of microorganism are more resistant to chemical and enzymatic degradation in the gastrointestinal tract. Such microorganisms are capable of binding TNFα and therefore reducing the content of free TNFα and alleviating its pro-inflammatory effects in the gut. The invention also relates to the use of such microorganisms as medicament in the treatment of inflammatory bowel disease. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10729731-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11633435-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11129906-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10828356-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11180535-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9616114-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10449237-B1 |
| priorityDate |
2010-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |