| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12b63fa79e9bc6eedeea3cd269d38a24 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-711
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 |
| filingDate |
2007-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ad1df6eedff0503b42b20015c4b5731
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cd96e50a0d70b500c796dce29b65ca3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a98c4794cf06a2a7fe710600358204a |
| publicationDate |
2011-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7960540-B2 |
| titleOfInvention |
Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin |
| abstract |
Compositions and methods for modulating tumor proliferation in an individual are provided. The methods employ nucleolin-binding agents, such as aptamers. The aptamers of the present invention can be used to modulate the proliferation of malignant, dysplastic, hyperproliferative, and/or metastatic cells through interference with molecular interactions and functions of nucleolin in the tumor cell. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10857237-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11344633-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017095562-A1 |
| priorityDate |
1999-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |