Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c1bec4d9586f72ec003182dea7ea94fb |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-711 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-711 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2007-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24c488c1dcd018847ddfd75e1277196e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba99adba23daba0bffae979ddade8cd9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70bd580c42df6ee7e59c4038326b0af2 |
publicationDate |
2008-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2008318890-A1 |
titleOfInvention |
Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin |
abstract |
Compositions and methods for modulating tumor proliferation in an individual are provided. The methods employ nucleolin-binding agents, such as aptamers. The aptamers of the present invention can be used to modulate the proliferation of malignant, dysplastic, hyperproliferative, and/or metastatic cells through interference with molecular interactions and functions of nucleolin in the tumor cell. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8114850-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011178161-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8648051-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7960540-B2 |
priorityDate |
1999-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |