| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_321601ebffa1b60386256ef6ac8b08ec |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-345
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-829 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1135
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1272
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-88 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2000-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2001-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9567a8e911e416b3d91965222f551fd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84e23dc99951e34c5e91afcd56cad147
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e0f6e1562459501340600f36a11c3b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27a027ff74651eddce60039e730a1c01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab98375d5e08af3b57dda321cb16500e |
| publicationDate |
2001-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6333314-B1 |
| titleOfInvention |
Liposomes containing oligonucleotides |
| abstract |
It is possible to radiosensitize tumor cells by administration of compositions containing the Human antisense c-raf-1 oligodeoxyribonucleotide (ODN/oligo) sequence: 5′-GTGCTCCATTGATGC-3′ (seq. ID No. 1) wherein only the end bases are phosphorylated is a preferred embodiment. Antisense sequences of up to 40 bases which containing this sequence may be used in accord with the teachings of this disclosure. Compositions comprising a cationic liposome of dimethyldioctadecyl ammonium bromide, phosphatidylcholine and cholesterol may be used as a carrier system. The liposomes provide a new carrier system that is particularly useful for administration of sequences for therapy. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7122553-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006099652-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003229040-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7960540-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7390502-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005266068-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003225023-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006034908-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011104252-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004161775-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7253272-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7351811-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005260260-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7442520-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004115714-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005153297-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005249795-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003215489-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006165744-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006182793-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8648051-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7244565-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004248218-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003215492-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003228317-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004228911-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8114850-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7262173-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005277611-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005002918-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7138512-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006078560-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006141020-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005181037-A1 |
| priorityDate |
1997-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |