| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66e14c7894b9649752ba93595b558634 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-18 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0655
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3852
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3608
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3683
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3817
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3654
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3895 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-10 |
| filingDate |
2006-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2010-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b817ce91bfa0828e25614f27fd3bd00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55fde95d50b0ae685f42006d71322bda |
| publicationDate |
2010-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7815926-B2 |
| titleOfInvention |
Implant for articular cartilage repair |
| abstract |
An implant for articular cartilage repair includes (1) a three-dimensional body formed of cancellous bone having a demineralized section that contains bone morphogenetic proteins (BMP's) that are released by the demineralization but retained in the body, and (2) a cartilage layer formed on a surface of the demineralized section. The cartilage layer is formed by a method including the steps of (a) isolating chondrocytes from articular cartilage of a donor; (b) cultivating the isolated chondrocytes in a medium; (c) suspending the cultivated chondrocytes in agarose; (d) adding the cultivated chondrocytes to the demineralized section of the body, whereby the cultivated chondrocytes are stimulated by the BMP's retained in the body; and (e) incubating the cultivated chondrocytes to form a plurality of layers of chondrocytes on the demineralized section, wherein the plurality of layers of chondrocytes forms the cartilage layer. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10617526-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9486556-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010241228-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8551525-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9364328-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11052175-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11452796-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10207030-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9730796-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11123193-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9889235-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8685432-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9289452-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9808558-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9603710-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9814803-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8906110-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10335281-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE43258-E
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8292968-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9220596-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009324683-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11229725-B2 |
| priorityDate |
2005-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |