| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12030ffbc539df5b155e08d951f57a7c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-495
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-425
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1875
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-495
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
| filingDate |
2005-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2008-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcfe04ae6eedde1fa9f4f5e6de3a0e97
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75db2d22d69b9efe604fe9eead96317f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5c7be136aae854c2407e02e73a2730e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_240397e62ca2d8775e28a567fe8d7c07 |
| publicationDate |
2008-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7365051-B2 |
| titleOfInvention |
Compounds with improved cartilage-inducing and/or bone-inducing activity |
| abstract |
The present invention concerns a bioactive implant material having a cartilage-inducing and/or bone-inducing activity composed of two components A and B, of which A is a bone-inducing and/or cartilage-inducing protein or protein mixture and preferably one or several proteins from the TGF-β superfamily, preferably MP52 or a DNA sequence coding therefor and B is a carrier matrix composed of calcium phosphate ceramics with an interconnecting microporosity which already alone has bone-inducing properties. The invention additionally concerns the production of these compounds and their use for the treatment of diseases which affect cartilage and/or bones as well as to treat damage to cartilage and/or bone tissue. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008255676-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8221500-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8906110-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10077420-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011142490-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7815926-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009069901-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7901457-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8292968-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9701940-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8435551-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010047299-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7837740-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE42208-E
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11555172-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10836807-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE43258-E |
| priorityDate |
1996-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |