| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_81c150af8961fd5ae4f74c3565019f3d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-48 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
| filingDate |
2001-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_308d7934c3ae064491a89bacdb9bea13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_172c66beff9239beee446ca31bea2c74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c803e3379bf808e29c405ae3a52843bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_210f9ff86b499846aee09b1e825eafb2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36c659d0097c83126043583470487372
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b15dba5f2c8183166392e70037ce4a4 |
| publicationDate |
2003-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6656718-B2 |
| titleOfInvention |
Modified carboxypeptidase enzymes and their use |
| abstract |
The invention relates to improvements relating to cancer therapy based on the identification of a number of regions of CPG2 which contain epitopes which appear to be involved in the production of a host immune response and which may be modified to alter the immunogenicity in patients. Production of fusions of CPG2 with an antibody, where the CPG2 protein has been tagged provides a CPG2 protein which has reduced immunogenicity. By using partially glycosylated enzyme obtainable by P. pastoris expression, the efficacy of antibody-CPG2 fusions is enhanced. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7977081-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008311619-A1 |
| priorityDate |
2000-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |