| abstract |
Dipeptidyl peptidase IV (DP 4) inhibiting compounds are provided having the formula n where n x is 0 or 1 and y is 0 or 1 (provided that n x=1 when y=0 and x=0 when y=1); n n is 0 or 1; X is H or CN; n and wherein R 1 , R 2 , R 3 and R 4 are as described herein. n A method is also provided for treating diabetes and related diseases, especially Type II diabetes, and other diseases as set out herein, employing such DP 4 inhibitor *or a combination of such DP 4 inhibitor and one or more of another antidiabetic agent such as metformin, glyburide, troglitazone, pioglitazone, rosiglitazone and/or insulin and/or one or more of a hypolipidemic agent and/or anti-obesity agent and/or other therapeutic agent. |