| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2eb7163c43f7e5c8a870f30f7f1cd5ea |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-785
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-785 |
| filingDate |
1999-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2001-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfd2cbb00a36da58556b261da0295538
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_782b54c2ec5885da5cfe29aed9c8b54e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdef79e2ad8fc9186c4b77575a4ef9c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56fa2e88bd6583f1bd70caaf84a73918 |
| publicationDate |
2001-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6264938-B1 |
| titleOfInvention |
Combination therapy for treating hypercholestrolemia |
| abstract |
The invention relates to methods for treating hypercholesterolemia and atherosclerosis, and reducing serum cholesterol in a mammal. The methods of the invention comprise administering to a mammal a first amount of a bile acid sequestrant compound which is an unsubstituted polydiallylamine polymer and a second amount of an HMG Co-A reductase inhibitor compound. The first and second amounts together comprise a therapeutically effective amount.The invention further relates to pharmaceutical compositions useful for the treatment of hypercholesterolemia and atherosclerosis, and for reducing serum cholesterol. The pharmaceutical compositions comprise a combination of a first amount of an unsubstituted polydiallylamine polymer compound and a second amount of an HMG Co-A reductase inhibitor compound. The first and second amounts comprise a therapeutically effective amount. The pharmaceutical compositions of the present invention may optionally contain a pharmaceutically acceptable carrier. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012027331-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11376251-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010014541-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002155091-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004018235-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10512657-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008118572-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11229661-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010266526-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6441022-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7638524-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10555969-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010014541-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6420417-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03013608-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005106267-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11083748-B2 |
| priorityDate |
1997-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |