| abstract |
The present invention is directed to polymeric- prodrug transport forms of the formula: ##STR1## wherein: B is a leaving group, OH, a residue of a hydroxyl-containing moiety or ##STR2## wherein B 1 is a leaving group, OH or a residue of a hydroxyl-containing moiety; n Y 1-2 are independently O or S; n M is selected from either X or Q; wherein X is an electron withdrawing group and Q is a moiety containing a free electron pair positioned three to six atoms from C(═Y 2 ); R 2-5 are independently selected from the group consisting of hydrogen, C 1-6 alkyls, C 3-12 branched alkyls, C 3-8 cycloalkyls, C 1-6 substituted alkyls, C 3-8 substituted cycloalkyls, aryls, substituted aryls, aralkyls, C 1-6 heteroalkyls and substituted C 1-6 heteroalkyls; n (m) is zero or one; n (n) is a positive integer; n (p) is zero or a positive integer; n Z is an electron withdrawing group; and n R 1 is a polymeric residue which is optionally capped with a moiety of the Formula (v) ##STR3## |