abstract |
The present invention relates to a novel pH triggered, targeted controlled release system. The controlled delivery system of the present invention is substantially a free-flowing powder formed of solid hydrophobic nanospheres comprising pharmaceutical active ingredients that are encapsulated in pH sensitive microspheres. The invention also relates to the processes for preparing the compositions and processes for using same. The controlled release system can be used to target and control the release of active ingredients for treating a cellular proliferation disease or tumors. The invention further pertains to pharmaceutical products comprising the controlled release system of the present invention. |