http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6130219-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-088 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-092 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-08 |
| filingDate | 1999-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2000-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_629216a700af8b82060670364e41764e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49e8c0b708b3dd8a27175be5d4e18a56 |
| publicationDate | 2000-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6130219-A |
| titleOfInvention | Drug resistance and multidrug resistance modulators |
| abstract | Drug and multidrug resistant modulators of the formula: where R1 and R2 are independently hydrogen or halo; A is -CH2-CH2-, -CH2-CHR4-CH2-, or -CH2-CHR5-CHR6-CH2-, where R4 is -H, -OH, or acyloxy; one of R5 or R6 is -H, -OH, or acyloxy, and the other is -H; R3 is a polyaryl; and pharmaceutically acceptable salts and solvates thereof, are described and claimed. Use of the new compounds in the preparation of pharmaceutical compositions is described and claimed. In addition, methods for treating drug and multidrug resistance in various diseases using a compound, or pharmaceutically acceptable salt or solvate thereof, of this invention are described and claimed. Also, methods of enhancing oral bioavailability of a drug and methods of enhancing bioavailability of a drug to the brain using a compound, or pharmaceutically acceptable salt or solvate thereof, of this invention are described and claimed. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003109448-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005119337-A1 |
| priorityDate | 1996-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 439.