abstract |
Novel heterocyclic compounds, which are represented by the following general formula (I), useful as anticancer drug potentiaters having a potentiating effect on the incorporation of anticancer drugs into cancer cells, the compounds each synthesized by, for example, reacting a epoxy compound obtained by reacting a heterocyclic compound with an epihalogenohydrin, with an amine derivative. An example is 5-[3-{4-(dibenzosuberane-5-yl)plperazine-1-yl}-z-hyroxypropoxy]quinoline. |