| abstract |
This invention is directed to certain 1,3- and 2,3-diarylpyrazole antiinflammatory compounds of the general formulae: wherein R1 and R2 are independently selected from the group consisting of hydrogen, halogen, (C1-C6)alkyl, (C1-C6)alkoxy, nitro, amino, hydroxy, trifluoro, -S(C1-C6)alkyl, -SO(C1-C6)alkyl and -SO2(C1-C6)alkyl and the fused moiety Q is a group selected from the group consisting of an optionally substituted cyclohexyl and cycloheptyl group as herein described, pharmaceutical compositions containing the compounds, processes for their production and use as COX-2 inhibitor and antiinflammatory agents. |