http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2159479-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ee46356e4404b1463eac34cf69ab734e |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-416 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-56 |
| filingDate | 1999-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0511c37e31ddb94eef3b0421765ba43c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e6bc8563f94a49027ef76a0cd55b0e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f99b446a90ea74518a22aeb29ff39161 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbddc2c284e7fa95444bbc8c48e575eb |
| publicationDate | 2001-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2159479-A1 |
| titleOfInvention | NEW INDAZOLS AS INHIBITORS OF CICLOOXIGENASA-II |
| abstract | New indazoles as cyclooxygenase-II inhibitors. The present invention relates to compounds of general formula I, **FORMULA**, selective inhibitors of cyclooxygenase-II, in which group A is a single bond, -O-, -S- or -NH-; R{sup,3} is hydrogen, (C{sub,1}- C{sub,12})-alkyl, (C{sub,2} C{sub,12})-alkenyl, (C{sub,2 }-C{sub,12})-alkynyl, (C{sub,1}-C{sub,12})-haloalkyl, (C{sub,1}-C{sub,12})-alkylcarbonyl, etc, to their pharmaceutically acceptable salts and solvates, and to pharmaceutical compositions containing them. The compounds of the present invention are useful in the treatment of inflammation, pain, and fever, as well as those other conditions that have recently been associated with cyclooxygenases, especially cyclooxygenase-II, such as colorectal cancer and Alzheimer's disease. Similarly, the present invention relates to a process for the preparation of the compounds, as well as their therapeutic use. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008053031-A1 |
| priorityDate | 1999-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.