http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109020890-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-54 |
filingDate | 2018-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-109020890-B |
titleOfInvention | Preparation and application of saturated aliphatic cyclo-pyrazole derivatives |
abstract | The invention discloses a preparation method of a novel tubulin inhibitor saturated fat cyclopyrazole derivative and application thereof in the aspect of tumor resistance. Has a structure shown in formula I: wherein: n is selected from 1, 2 and 3; r 1 Selected from: -H, -OCH 3 ;R 2 Selected from: -H, -Cl, -OCH 3 ;R 3 Selected from: -H, -OCH 3 ;R 4 Selected from: -H, -F, -OH, -CH 3 、‑OCH 3 ;R 5 Selected from: -H, -F, -Cl, -Br, -I, -CH 3 、‑CF 3 、‑OCH 3 、‑COOH、‑NO 2 、‑OH;R 6 Selected from: -H, -OCH 3 。 |
priorityDate | 2018-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 95.