| abstract |
A bandage for use in the continuous administration of drugs to the skin or mucosa, comprising a backing member defining one exterior surface, a surface of pressure-sensitive adhesive defining a second exterior surface, and disposed therebetween a reservoir containing drug formulation confined therein. The reservoir can comprise a distinct layer of the bandage or a plurality of microcapsules distributed throughout the adhesive surface, and in either case the drug can be confined within an interior chamber of the reservoir or distributed throughout a reservoir matrix. The drug passes through drug release rate controlling microporous material which continuously meters the flow of drug by viscous or diffusive transfer to the skin or mucosa at a controlled and predetermined rate over a period of time. |