Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_31f87c170ea6e478544c388bd11bb684 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_30a34ce1258e2b64857af06427363443 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2205-0244 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2037-0023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2037-0007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2037-0061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2037-0053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2037-003 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-306 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1793 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M37-0015 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N1-30 |
filingDate |
2011-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2017-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23838677ef24bde46c4781a88b296b65 |
publicationDate |
2017-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9586044-B2 |
titleOfInvention |
Method for increasing the permeability of an epithelial barrier |
abstract |
Disclosed are nanotopography-based methods and devices for interacting with a component of epithelial tissue and increasing the permeability of the tissue. Devices include structures fabricated on a surface to form a nanotopography. A random or non-random pattern of structures may be fabricated such as a complex pattern including structures of differing sizes and/or shapes. Microneedles may be beneficially utilized for delivery of an agent to a cell or tissue. Devices may be utilized to directly or indirectly alter cell behavior through the interaction of a fabricated nanotopography with the components of epithelial tissue. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10039565-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10973682-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10987119-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-D868246-S |
priorityDate |
2010-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |