| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e41651508566f0385833e1ba14a21ffd |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-26003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate |
2009-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8baef1b037ecace01acf26e1de8997f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac080fc8148277dfd0c9421bb3449a2f |
| publicationDate |
2010-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2010075423-A1 |
| titleOfInvention |
Methods and compositions relating to polypeptides with rnase iii domains that mediate rna interference |
| abstract |
The present invention concerns methods and compositions involving RNase III and polypeptides containing RNase III domains to generate RNA capable of triggering RNA-mediated interference (RNAi) in a cell. In some embodiments, the RNase III is from a prokaryote. RNase III activity will cleave a double-stranded RNA molecule into short RNA molecules that may trigger or mediate RNAi (siRNA). Compositions of the invention include kits that include an RNase III domain-containing polypeptide. The present invention further concerns methods using polypeptides with RNase III activity for generating RNA molecules that effect RNAi, including the generation of a number of RNA molecules to the same target. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9592250-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9796978-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9777275-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010184039-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8524680-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10626398-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010221789-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010136695-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10106793-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10196640-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010298408-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004029275-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009023216-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8815821-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10036025-B2 |
| priorityDate |
2002-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |