| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b2635ac0b864e7968f41c6c1b6f6e77
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ccca26c25c144e42e8644a42d6483d4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf9ede3d85d65de9f36f769cee834a01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5d92ebdbaf4711aee8cf5c153eee337c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-085 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4716
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4747
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-475
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-525
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-567
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 |
| filingDate |
2006-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d3207246965ba55628364f2325e047a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36f53075d9fac3a33c33d39eb76f17b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc274d394ccffbb38e171551d7c3a73f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7fdd278668c7c0313e3ed5f2a1455bc |
| publicationDate |
2006-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2006275838-A1 |
| titleOfInvention |
Compositions and methods for inhibiting liver stellate cell growth |
| abstract |
The present invention provides compositions and methods for selectively inhibiting the proliferation of stellate cells, which are important for the development of liver fibrosis upon liver injury. The invention describes conditioned media from immortalized hepatocytes as containing a death factor that induces apoptosis of activated liver stellate cells. This pro-apoptotic activity is shown to be associated with the peptide sequence of the actin depolymerizing molecule gelsolin and or fragments thereof. The apoptotic activity is increased upon incubation of immunoglobulins with the stellate death factor. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114831961-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021113657-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9011938-B2 |
| priorityDate |
2003-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |