abstract |
This invention characterizes the selective apoptotic activity of specially prepared Alpha2 and fragments thereof. Specifically, Alpha2 which has been overloaded with zinc, as well as fragments thereof, selectively induce apoptosis in HT-29 (colon cancer), LNCaP (prostate cancer), and Hep G2 (Hepatoma) cells, while having no affect on CCD 18 Co (normal colon) cells. |