abstract |
An intravascular, indwelling instrument for placement in a blood vessel includes a body having a face in contact with a maintained blood flow to be maintained and a face in contact with a non-maintained blood flow not to be maintained, and a peptide fixed to all or part of the maintained blood flow contact face or the non-maintained blood flow contact face of the body. The peptide has specific interaction with vascular endothelial precursor cells, with the peptide permitting selective adsorption and adhesion of the vascular endothelial precursor cells to cover all or part of the maintained blood flow contact face or the non-maintained blood flow contact face of the body with the vascular endothelial precursor cells thereby reducing or inhibiting the blood flow not to be maintained. |