Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_029116ee41eeec8a03f88a8cddbaa758 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_611a62ef7f772f233f150d8fe41ea0f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b65d454a932976fa2078481424563b4b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_caf2da0e942b97067f9dcdfc309ba9c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d49230aee3f8992f7f483f37c4b1c75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e496fa946ef620b52e204ad8d2e5a845 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-608 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-252 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-148 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-14 |
filingDate |
2007-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_895457aed719836215e94021e2d80423 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_274679db0d3731ab421973da82a5d4b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8f1507d2fe0a35a20fc535369651176 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_041392fd59f34991c22e10ae41b517d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b73335ba200232666b7b5ba171a5ce6 |
publicationDate |
2008-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2008030388-A2 |
titleOfInvention |
Medical devices having a coating for promoting endothelial cell adhesion |
abstract |
A medical device having a coating of cell adhesion polypeptides to enhance endothelial cell adhesion onto the medical device. The cell adhesion polypeptides may be any of the proteins of the extracellular matrix which are known to play a role in cell adhesion or derivative peptides such as RGD or YlGSR. The polypeptides may be incorporated into the backbone of polymer such as polyurethane, or grafted onto a polymer such polybisphosphonate. The polypeptides may also be carried on antibodies or displayed on bacteriophages. The polypeptides may also be modified to have adhesive amino acid sequences. In certain embodiments, the medical device further comprises a temporary barrier that protects the polypeptides from biofouling. The temporary barrier may be formed of a biodegradable polymer and be constructed as a coating over the polypeptides or as a plurality o micelles encapsulating the polypeptides. In certain embodiments, the polypeptides may be coated onto the medical device in such a manner as to form a monolayer of the polypeptides. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11253626-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2744460-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9463262-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008143933-A1 |
priorityDate |
2006-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |