| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_029116ee41eeec8a03f88a8cddbaa758 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-252
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-608 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-047
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-148
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B05D3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-02 |
| filingDate |
2007-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ab7391914ffb2aba51b1d654b443441
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17c50402d8cadec4a427e6498a2ef868
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72d97cdb093a5b370fe2f1d013132240
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04fb802d47976d0fc508f5e9a2d2f2fd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb6fe67e4f2b46c447c3949aa8b68b3f |
| publicationDate |
2008-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2008057097-A1 |
| titleOfInvention |
Medical devices having a coating for promoting endothelial cell adhesion |
| abstract |
A medical device having a coating of cell adhesion polypeptides to enhance endothelial cell adhesion onto the medical device. The cell adhesion polypeptides may be any of the proteins of the extracellular matrix which are known to play a role in cell adhesion or derivative peptides such as RGD or YIGSR. The polypeptides may be incorporated into the backbone of a polymer such as polyurethane, or grafted onto a polymer such polybisphosphonate. The polypeptides may also be carried on antibodies or displayed on bacteriophages. The polypeptides may also be modified to have adhesive amino acid sequences. In certain embodiments, the medical device further comprises a temporary barrier that protects the polypeptides from biofouling. The temporary barrier may be formed of a biodegradable polymer and be constructed as a coating over the polypeptides or as a plurality of micelles encapsulating the polypeptides. In certain embodiments, the polypeptides may be coated onto the medical device in such a manner as to form a monolayer of the polypeptides. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8574612-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020230286-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2475468-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7927414-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010226953-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010058952-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007173922-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010022940-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007179589-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011045055-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010063539-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11253626-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009018642-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110292654-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8858698-B2 |
| priorityDate |
2006-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |