Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76ba102ea9c02b6633d64bf09c5b89a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e3830f35387a1c32061dea3ee310851 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-531 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 |
filingDate |
2017-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2021-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1697ed9c00d0957502d68e6d468257c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_159b336d1791db653bd7d4662c5267d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79e04f171d49008bcee939d721e9d8bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c56e3ae2c6a571687924729cbd069b00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fb4c62ca1a2ecd6613758f570eefd4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eaf416435c934928f979ee9ef4c66a03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7f0d24e04714cf793edc798b6db14b2 |
publicationDate |
2021-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-11118185-B2 |
titleOfInvention |
AAV vectors for treatment of dominant retinitis pigmentosa |
abstract |
Aspects of the disclosure relate to methods and compositions for treating retinitis pigmentosa. In some aspects, the disclosure provides compositions and methods for delivering an interfering nucleic acid (for example an interfering RNA) to a subject in order to reduce expression of one or both alleles of an endogenous rho gene (for example a mutant rho allele associated with retinitis pigmentosa) in the subject. In some embodiments, a replacement rho gene that is resistant to the interfering nucleic acid also is delivered to the subject. |
priorityDate |
2016-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |