http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2747087-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e8074387a869f32642d10ba0499f5ef6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-39 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38 |
| filingDate | 2020-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56bfec971816d937937e2d4632136b12 |
| publicationDate | 2021-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2747087-C1 |
| titleOfInvention | Method for production of biocomposite spheroids for bone restoration |
| abstract | FIELD: medicine.SUBSTANCE: invention relates to the field of medicine, namely to tissue engineering, regenerative medicine, plastic surgery, dentistry, traumatology and orthopedics, it consists in developing a method for producing spheroids for restoring the bone tissue of a subject. A method for obtaining spheroids for restoring the bone tissue of the subject includes obtaining adhesive cell cultures of autologous cells of the subject, which are 2D cell cultures; 3D cultivation of these autologous cells of the subject in agarose wells. As an agarose well, a truncated pyramid-shaped agarose well in the form of a quadrangular regular pyramid is used. The feed medium is supplied using an electron-mesh nebulizer in the form of a fine aerosol with a drop size of 1-3 mcm. The aerosol spray torch is directed at an angle of 20-85º to the base of the well, and the slope of the agarose wells to the horizon is 3-5º. The nutrient medium contains a defoamer.EFFECT: development of a new effective method for producing spheroids, in particular, on the basis of periosteal cells for the effective restoration of bones with a pronounced regenerative potential.10 cl, 1 ex, 2 dwg |
| priorityDate | 2020-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.