abstract |
The present invention provides a benzenesulfonamide compound represented by the formula (1) or a biotinylated compound thereof. The compounds of the present invention selectively react with unoxidized sulfhydryl groups (-SH) of cysteine, and exhibit the action and effect of not reacting with oxidative modifications. Therefore, the compound of the present invention can detect the sulfhydryl group of cysteine. In addition, the compounds of the present invention can measure the reactivity of each cysteine to the oxidation reaction, and thus can target the active oxygen target protein. |