| abstract |
In the present invention, the plum (Fructus) The present invention relates to a composition for the prevention or treatment of dementia containing the extract of Mume, wherein the ume extract of the present invention normalizes hippocampal damage induced by chronic vascular brain injury in an animal model of vascular dementia (ERK phosphorylation normalization, ChAT increase, NF). -kappa B normalization) and the effect of improving the spatial memory capacity, so it can be useful for medicines for the prevention or treatment of dementia diseases accompanied by vascular brain injury, such as vascular dementia, and health functional foods for the prevention or improvement of dementia diseases have. |