http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6192596-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01c1e0bc0628f76dea731cda5a666ca1 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
| filingDate | 1984-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c006a95a31a2cc3e42cc320eacfd228 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ea45cd80f9d955df0167686da0f4d62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8043c3660f369a10a36415466c0a9d84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c6769f8defd4fc938e1522235776f29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4129f3d50e5d64bcf5846c4dde5940e8 |
| publicationDate | 1986-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6192596-A |
| titleOfInvention | Immobilized enzyme, and production of optically active indoline-2-carboxylic acid therewith |
| abstract | PURPOSE:To produce optically active indoline-2-carboxylic acid efficiently and industrially, by subjecting an (R,S)-indoline-2-carboxylic acid ester to asymmetric hydrolysis with a specific immobilized enzyme. CONSTITUTION:An immobilized enzyme (immobilized microorganism may be used) having stereoselective esterase activity, supported on a hydrophobic carrier, is used. Namely, (i) an (R,S)-indoline-2-carboxylic acid ester shown by the formula I (R is 2-8C aliphatic hydrocarbon) is loaded into a column packed with the immobilized enzyme, (ii) a buffer solution is made to flow into it to carry out an asymmetric hydrolysis reaction, prepared hydrophilic optically active indoline-2-carboxylic acid shown by the formula II is eluted with a buffer solution, and recovered. Then, (iii) an organic solvent with low polarity (e.g., benzene, or hexane) is made to flow into it, an adsorbed hydrophobic indoline-2- carboxylic acid ester shown by the formula III is eluted and recovered. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0197474-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109762768-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007117034-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1687270-A4 |
| priorityDate | 1984-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.