| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1a48b04f986c44c2ca9129ce0b1d17c6 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-403
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 |
| filingDate |
1980-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c062a96f675ed6ac8817b423e49cb870
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cccfe942217a4a23a254dda804afc04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eafed4bef8ae45344163815ecb4ef144
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb4b5a24668d84066d70963339450f3a |
| publicationDate |
1982-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-S5781460-A |
| titleOfInvention |
Novel indolinecarboxylic acid derivative |
| abstract |
NEW MATERIAL:N-(3-Mercapto-2-methylpropionyl)-indoline-2-carboxylic acid of formula and its salt. n EXAMPLE: N-[3-Mercapto-2(S)-methylpropionyl]-indoline-2(R)-carboxylic acid. n USE: Hypotensor. It has extremely strong activity to inhibit angiotensin-I converting enzyme. n PROCESS: A mixture of four stereo-isomers of the compound of formula or N-[3- mercapto-2(S)-methylpropionyl]-1-indoline-2(R)-carboxylic acid is prepared e.g. by reacting indoline 2(R)-carboxylic acid ester with 3-acetylthio-2(S)-methylpropionyl chloride, and then hydrolyzing the reaction product. n COPYRIGHT: (C)1982,JPO&Japio |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0573396-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0578310-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6192595-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6192596-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S61227796-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10420761-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0648995-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014145386-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014145386-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S61282093-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0616718-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10835524-B2 |
| priorityDate |
1980-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |