abstract |
(57) [Summary] [Structure] Due to the action of microorganisms belonging to the genus Aureobacterium, (R)-(-)-3-halo-1,2-propane is converted from 1,3-dihalo-2-propanol or epihalohydrin. From 1,3-dihalo-2-propanol or epihalohydrin in the presence of a diol, cyanide (R)-(-)-4-halo-3-hydroxybutyronitrile, and from 1,3-dihalo-2-propanol A method for producing an optically active halohydrin such as (R) -epihalohydrin. [Effect] By using a microorganism, halohydrin having high optical purity can be efficiently produced from each substrate in one step. |