http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016510025-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-0812 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-24 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-24 |
filingDate | 2014-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2016510025-A |
titleOfInvention | Substituted (R) -3- (4-methylcarbamoyl-3-fluorophenylamino) tetrahydrofuran-3-enecarboxylic acid (variant) and its esters, process for preparation and use |
abstract | The present invention relates to novel chemical compounds of general formula 1 which are intermediate products of the synthesis of androgen receptor inhibitors of interest as anticancer drug formulations. The subject of the present invention further includes a process for preparing novel compounds of general formula 1.1 which are androgen receptor inhibitors. What is claimed is a substituted 3- (4-methylcarbamoyl-3-fluorophenylamino) tetrahydrofuran-3-enecarboxylic acid or ester of general formula 1 or 1.1, or a stereoisomer thereof. Wherein, in Formula 1, R 1 = C 1 -C 4 alkyl; R 2 = H, CH 2 OCH 2 CH 2 Si (CH 3 ) 3 ; and R 1 = H, C 1 -C 4 alkyl; R 2 = H, CH 2 OCH 2 CH 2 Si (CH 3 ) 3 . |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017522379-A |
priorityDate | 2013-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.